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Musclebots Take Some Steps

You've probably heard of robots. Now, make way for musclebots. Scientists in California have made tiny walking machines out of heart muscle grown from rat cells. When the muscle contracts, then relaxes, the musclebot takes a step. The entire device is tinier than a comma. Viewed under a microscope, "they move very fast," says bioengineer Jianzhong Xi of the University of California, Los Angeles (UCLA). "The first time I saw that, it was kind of scary." Scientists have already used muscle tissue to make machines, but these earlier machines were much larger than the new musclebots. A few years ago, for instance, a team at the Massachusetts Institute of Technology made a palm-sized device, called a biomechatronic fish, which swam by using living muscle tissue taken from frogs' legs. Adding muscles to a minuscule machine requires a different approach. Instead of using whole tissue, the scientists grew a thin film of heart muscle right on their bot. To do this, they borrowed some methods from the industry that makes chips for computers and other high-tech devices. But these methods can harm cells, so the team also invented some cell-friendly techniques to help do the job. In the end, the musclebot looks like a golden arch, coated on its inner surface with muscle. Kept alive in a special solution containing glucose, the heart muscle cells beat, causing the bot to scoot along. When the muscle contracts, the arch squeezes together, and the back leg moves forward. When the muscle relaxes, the arch widens, and the front leg moves forward. Researchers envision a number of applications for the new technology, including musclebots that deliver drugs directly to the cells that need them. They might also be useful for building other tiny machines, converting muscle motion into electric power for microcircuits, or studying muscle tissue. So far, musclebots can move only in one direction, and they can't be easily turned on and off. Future versions are sure to be more versatile.—E. Sohn

Musclebots Take Some Steps
Musclebots Take Some Steps

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