Add your Article
- Chemistry and Materials
- The newest superheavy in town
- These gems make their own way
- The hottest soup in New York
- Computers
- The Shape of the Internet
- Seen on the Science Fair Scene
- The Earth-bound asteroid scientists saw coming
- Dinosaurs and Fossils
- South America's sticky tar pits
- Early Birds Ready to Rumble
- Fossil Fly from Antarctica
- E Learning Jamaica
- E Learning in Jamaica WIN PRIZES and try our Fun Animated Games
- 2014 GSAT Results for Jamaican Kids
- Results of GSAT are in schools this week
- Environment
- Antarctica warms, which threatens penguins
- City Trees Beat Country Trees
- The Best Defense Is a Good Snow Fence
- Finding the Past
- The Puzzle of Ancient Mariners
- Unearthing Ancient Astronomy
- If Only Bones Could Speak
- GSAT Exam Preparation Jamaica
- GSAT stars reap scholarship glory
- How are students placed after passing the GSAT exam
- GSAT Practice Papers | GSAT Mathematics | Maths
- GSAT Exams Jamaica Scholarships
- GSAT Practice Papers | GSAT Mathematics | Maths
- 2014 GSAT Results for Jamaican Kids
- GSAT stars reap scholarship glory
- GSAT Mathematics
- Secrets of an Ancient Computer
- Math is a real brain bender
- Math and our number sense: PassGSAT.com
- Parents
- Raise a Lifelong Reader by Reading Aloud
- Choosing a Preschool: What to Consider
- Children and Media
- Plants
- City Trees Beat Country Trees
- Bright Blooms That Glow
- White fuzzy mold not as friendly as it looks
- Space and Astronomy
- Galaxies Divide Sharply Along Color Lines
- Saturn's Spongy Moon
- Ready, Set, Supernova
A Sour Taste in Your Mouth
Published: 07/05/2010
Think of all the amazing things that your tongue does for you. Specialized cells on your tongue, for example, give you the power to enjoy (and gag at) the spices and other flavors of the world’s cuisines.
For years, scientists have been investigating the cells that allow us to detect five distinct tastes: salty, sweet, bitter, sour, and umami. Umami describes the taste of a substance called monosodium glutamate (MSG). So far, sweet, bitter, and umami are pretty well understood. The other two have remained mysterious.
Now, at long last, researchers may have discovered the secret behind the puckering flavor of lemons, vinegar, and sour gummy candy. One protein, called PKD2L1, might do the trick.
To decode the sour system, the scientists started by assuming that sour-sensing proteins would share basic traits with proteins that allow us to sense other tastes. In general, these molecules, called receptors, are embedded inside certain tongue cells.
Also, each tongue cell contains a receptor that senses just one type of flavor. One cell might have a sweet receptor, for instance, while another cell responds only to bitter flavors.
The scientists zeroed in on PKD2L1. This protein caught their eye because it appeared to be a specialized protein in taste bud cells. At the same time, it did not show up in cells that sensed sweet, bitter, or umami flavors.
The researchers then created a strain of mice that did not make the PKD2L1 protein. Tests of the animals’ nerves showed that the mice continued to respond to all flavors except sour ones. When the scientists gave them sour chemicals, such as citric acid or vinegar, nothing happened.
The mice “were completely insensitive, just like we were dabbing their tongues with water,” says research-team leader Charles S. Zuker of the University of California, San Diego.
The discovery may eventually help chemists make foods more or less sour, from the inside out.
Here’s what I’d like to know next: Why do some people like to eat sour candy? I’m not a fan, and I never will be, but I know people who love it. The mysteries of science never cease to amaze me!—E. Sohn
A Sour Taste in Your Mouth
